Methotrexate Action Mechanism
Methotrexate results in the slowing down of the cancer progression by acting as an allosteric inhibitor of the enzyme dihydrofolate reductase, which plays a key role in production of certain building blocks essential for synthesis of DNA. As a result, this anti-cancer drug interferes with the synthesis of DNA as well as RNA in the cell and results its action in comparatively less time span.
Since, Methotrexate is a cancer medication it is recommended to follow your medical professional consultation with regards to its exact dosage. Do remember that this drug is not to be daily on daily basis as this is purely a weekly drug that is recommended either once a week or twice a week depending upon your clinical condition severity.
The ability of Methotrexate to effectively treat various other clinical conditions in addition to treating cancer forms its advantage. The other diseases that have been found to get cured in an efficient manner with the aid of this drug are psoriatic arthritis, multiple sclerosis, ectopic pregnancy as well as crohn’s disease.